Palmitoylethanolamide With Luteolina- 60 Capsules

PEA is found in nearly all animal tissues, human breast milk, and many foods. Our body produces PEA to protect and repair tissues and minimize pain. Since its discovery in 1957, PEA has been studied extensively for its anti-inflammatory, neuro-protective and analgesic properties.*

PEA occurs naturally in the body and in many foods. No side effects have been reported with its use, even at the highest doses.

Luteolin is a bioflavonoid with potent antioxidant and anti-inflammatory properties. It is naturally occurring in many foods including; artichoke, celery, parsley and peanuts.

Like PEA, luteolin has several mechanisms of action. It inhibits mast cells, as well as mast cell-dependent T cell activation. Luteolin modulates microglial activation and inhibits pro-inflammatory cytokine production. It also acts on GABA and opioid receptors in the spinal cord.*

The combination of PEA with luteolin has been shown to decrease mast cell activation significantly more than PEA or luteolin alone, and to reduce pro-inflammatory cytokines (TNF-alpha, IL-1 beta, IL-6) and chemokines (MIP-1 alpha, MIP-2) significantly more than PEA or luteolin alone. Additionally, PEA with luteolin was shown to reduce oxidative and nitrosative damage more effectively than PEA or luteolin alone.*